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Ytterbium in PDB 3fts: Leukotriene A4 Hydrolase in Complex with Resveratrol

Enzymatic activity of Leukotriene A4 Hydrolase in Complex with Resveratrol

All present enzymatic activity of Leukotriene A4 Hydrolase in Complex with Resveratrol:
3.3.2.6;

Protein crystallography data

The structure of Leukotriene A4 Hydrolase in Complex with Resveratrol, PDB code: 3fts was solved by D.R.Davies, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.00 / 2.33
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 78.028, 87.180, 98.750, 90.00, 90.00, 90.00
R / Rfree (%) 17.8 / 23.4

Other elements in 3fts:

The structure of Leukotriene A4 Hydrolase in Complex with Resveratrol also contains other interesting chemical elements:

Zinc (Zn) 1 atom

Ytterbium Binding Sites:

The binding sites of Ytterbium atom in the Leukotriene A4 Hydrolase in Complex with Resveratrol (pdb code 3fts). This binding sites where shown within 5.0 Angstroms radius around Ytterbium atom.
In total only one binding site of Ytterbium was determined in the Leukotriene A4 Hydrolase in Complex with Resveratrol, PDB code: 3fts:

Ytterbium binding site 1 out of 1 in 3fts

Go back to Ytterbium Binding Sites List in 3fts
Ytterbium binding site 1 out of 1 in the Leukotriene A4 Hydrolase in Complex with Resveratrol


Mono view


Stereo pair view

A full contact list of Ytterbium with other atoms in the Yb binding site number 1 of Leukotriene A4 Hydrolase in Complex with Resveratrol within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Yb702

b:27.4
occ:1.00
OXT A:ACT801 2.3 25.2 1.0
OD1 A:ASP481 2.5 19.7 1.0
OD2 A:ASP481 2.5 22.2 1.0
O A:HOH841 2.6 13.5 1.0
O A:HOH628 2.7 14.5 1.0
CG A:ASP481 2.8 20.9 1.0
C A:ACT801 3.1 24.8 1.0
O A:ACT801 3.2 24.9 1.0
O A:HOH842 3.3 24.2 1.0
OD2 A:ASP482 4.3 14.7 1.0
O A:HOH671 4.3 10.1 1.0
CB A:ASP481 4.4 19.4 1.0
O A:HOH1029 4.4 15.0 1.0
OD1 A:ASP482 4.5 20.1 1.0
CH3 A:ACT801 4.6 22.8 1.0
CG A:ASP482 4.7 17.2 1.0
CB A:LYS479 4.9 15.6 1.0

Reference:

D.R.Davies, B.Mamat, O.T.Magnusson, J.Christensen, M.H.Haraldsson, R.Mishra, B.Pease, E.Hansen, J.Singh, D.Zembower, H.Kim, A.S.Kiselyov, A.B.Burgin, M.E.Gurney, L.J.Stewart. Discovery of Leukotriene A4 Hydrolase Inhibitors Using Metabolomics Biased Fragment Crystallography. J.Med.Chem. V. 52 4694 2009.
ISSN: ISSN 0022-2623
PubMed: 19618939
DOI: 10.1021/JM900259H
Page generated: Wed Dec 16 02:41:37 2020

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