Atomistry » Ytterbium » PDB 1c5k-3fty » 3b7u
Atomistry »
  Ytterbium »
    PDB 1c5k-3fty »
      3b7u »

Ytterbium in PDB 3b7u: Leukotriene A4 Hydrolase Complexed with Kelatorphan

Enzymatic activity of Leukotriene A4 Hydrolase Complexed with Kelatorphan

All present enzymatic activity of Leukotriene A4 Hydrolase Complexed with Kelatorphan:
3.3.2.6;

Protein crystallography data

The structure of Leukotriene A4 Hydrolase Complexed with Kelatorphan, PDB code: 3b7u was solved by F.Tholander, J.Haeggstrom, M.Thunnissen, A.Muroya, B.-P.Roques, M.-C.Fournie-Zaluski, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 14.67 / 1.90
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 77.829, 87.136, 99.191, 90.00, 90.00, 90.00
R / Rfree (%) 17 / 21.7

Other elements in 3b7u:

The structure of Leukotriene A4 Hydrolase Complexed with Kelatorphan also contains other interesting chemical elements:

Zinc (Zn) 1 atom

Ytterbium Binding Sites:

The binding sites of Ytterbium atom in the Leukotriene A4 Hydrolase Complexed with Kelatorphan (pdb code 3b7u). This binding sites where shown within 5.0 Angstroms radius around Ytterbium atom.
In total 3 binding sites of Ytterbium where determined in the Leukotriene A4 Hydrolase Complexed with Kelatorphan, PDB code: 3b7u:
Jump to Ytterbium binding site number: 1; 2; 3;

Ytterbium binding site 1 out of 3 in 3b7u

Go back to Ytterbium Binding Sites List in 3b7u
Ytterbium binding site 1 out of 3 in the Leukotriene A4 Hydrolase Complexed with Kelatorphan


Mono view


Stereo pair view

A full contact list of Ytterbium with other atoms in the Yb binding site number 1 of Leukotriene A4 Hydrolase Complexed with Kelatorphan within 5.0Å range:
probe atom residue distance (Å) B Occ
X:Yb702

b:11.9
occ:1.00
O X:HOH747 2.3 3.4 1.0
OD2 X:ASP481 2.3 7.3 1.0
OXT X:ACY706 2.4 5.7 1.0
O X:HOH771 2.4 6.7 1.0
OD1 X:ASP481 2.5 8.2 1.0
O X:ACY706 2.5 6.8 1.0
C X:ACY706 2.8 6.9 1.0
CG X:ASP481 2.8 11.2 1.0
O X:HOH741 4.2 4.8 1.0
CH3 X:ACY706 4.3 6.6 1.0
CB X:ASP481 4.3 9.1 1.0
OD2 X:ASP482 4.4 11.5 1.0
OD1 X:ASP482 4.4 12.5 1.0
CG X:ASP482 4.8 13.7 1.0
CB X:LYS479 4.8 5.8 1.0
CG X:LYS479 4.8 9.8 1.0

Ytterbium binding site 2 out of 3 in 3b7u

Go back to Ytterbium Binding Sites List in 3b7u
Ytterbium binding site 2 out of 3 in the Leukotriene A4 Hydrolase Complexed with Kelatorphan


Mono view


Stereo pair view

A full contact list of Ytterbium with other atoms in the Yb binding site number 2 of Leukotriene A4 Hydrolase Complexed with Kelatorphan within 5.0Å range:
probe atom residue distance (Å) B Occ
X:Yb703

b:22.2
occ:0.25
O X:HOH1085 2.8 36.7 1.0
O X:ASP610 3.5 39.9 1.0
CA X:ASP610 4.0 39.2 1.0
C X:ASP610 4.2 40.0 1.0
N X:ASP610 4.3 36.3 1.0
OD1 X:ASP610 4.6 41.6 1.0

Ytterbium binding site 3 out of 3 in 3b7u

Go back to Ytterbium Binding Sites List in 3b7u
Ytterbium binding site 3 out of 3 in the Leukotriene A4 Hydrolase Complexed with Kelatorphan


Mono view


Stereo pair view

A full contact list of Ytterbium with other atoms in the Yb binding site number 3 of Leukotriene A4 Hydrolase Complexed with Kelatorphan within 5.0Å range:
probe atom residue distance (Å) B Occ
X:Yb704

b:18.9
occ:0.25
OD2 X:ASP175 2.1 29.3 1.0
CG X:ASP175 3.3 22.7 1.0
OD1 X:ASP175 3.9 26.2 1.0
CB X:ASP175 4.5 17.3 1.0
CA X:ASP175 4.7 17.1 1.0
O X:ASP175 4.7 20.0 1.0
C X:ASP175 5.0 18.2 1.0

Reference:

F.Tholander, A.Muroya, B.P.Roques, M.C.Fournie-Zaluski, M.M.Thunnissen, J.Z.Haeggstrom. Structure-Based Dissection of the Active Site Chemistry of Leukotriene A4 Hydrolase: Implications For M1 Aminopeptidases and Inhibitor Design. Chem.Biol. V. 15 920 2008.
ISSN: ISSN 1074-5521
PubMed: 18804029
DOI: 10.1016/J.CHEMBIOL.2008.07.018
Page generated: Sat Oct 12 21:02:42 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy