Atomistry » Ytterbium » PDB 1c5k-3fty » 3b7r
Atomistry »
  Ytterbium »
    PDB 1c5k-3fty »
      3b7r »

Ytterbium in PDB 3b7r: Leukotriene A4 Hydrolase Complexed with Inhibitor RB3040

Enzymatic activity of Leukotriene A4 Hydrolase Complexed with Inhibitor RB3040

All present enzymatic activity of Leukotriene A4 Hydrolase Complexed with Inhibitor RB3040:
3.3.2.6;

Protein crystallography data

The structure of Leukotriene A4 Hydrolase Complexed with Inhibitor RB3040, PDB code: 3b7r was solved by F.Tholander, J.Haeggstrom, M.Thunnissen, A.Muroya, B.-P.Roques, M.-C.Fournie-Zaluski, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 15.53 / 1.81
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 78.330, 86.937, 99.109, 90.00, 90.00, 90.00
R / Rfree (%) 14.9 / 18.5

Other elements in 3b7r:

The structure of Leukotriene A4 Hydrolase Complexed with Inhibitor RB3040 also contains other interesting chemical elements:

Zinc (Zn) 1 atom

Ytterbium Binding Sites:

The binding sites of Ytterbium atom in the Leukotriene A4 Hydrolase Complexed with Inhibitor RB3040 (pdb code 3b7r). This binding sites where shown within 5.0 Angstroms radius around Ytterbium atom.
In total only one binding site of Ytterbium was determined in the Leukotriene A4 Hydrolase Complexed with Inhibitor RB3040, PDB code: 3b7r:

Ytterbium binding site 1 out of 1 in 3b7r

Go back to Ytterbium Binding Sites List in 3b7r
Ytterbium binding site 1 out of 1 in the Leukotriene A4 Hydrolase Complexed with Inhibitor RB3040


Mono view


Stereo pair view

A full contact list of Ytterbium with other atoms in the Yb binding site number 1 of Leukotriene A4 Hydrolase Complexed with Inhibitor RB3040 within 5.0Å range:
probe atom residue distance (Å) B Occ
L:Yb801

b:14.3
occ:1.00
O L:HOH1609 2.2 13.1 1.0
O L:HOH1444 2.4 9.5 1.0
O L:HOH1447 2.4 15.7 1.0
OD1 L:ASP481 2.4 10.6 1.0
OD2 L:ASP481 2.5 10.7 1.0
O L:HOH1543 2.6 18.4 1.0
CG L:ASP481 2.8 11.1 1.0
CB L:ASP481 4.3 11.6 1.0
OD2 L:ASP482 4.3 12.2 1.0
OD1 L:ASP482 4.4 13.7 1.0
O L:HOH1437 4.5 33.1 1.0
CG L:ASP482 4.7 13.0 1.0
CB L:LYS479 4.8 12.4 1.0
CG L:LYS479 4.9 17.0 1.0

Reference:

F.Tholander, A.Muroya, B.P.Roques, M.C.Fournie-Zaluski, M.M.Thunnissen, J.Z.Haeggstrom. Structure-Based Dissection of the Active Site Chemistry of Leukotriene A4 Hydrolase: Implications For M1 Aminopeptidases and Inhibitor Design. Chem.Biol. V. 15 920 2008.
ISSN: ISSN 1074-5521
PubMed: 18804029
DOI: 10.1016/J.CHEMBIOL.2008.07.018
Page generated: Sat Oct 12 21:01:27 2024

Last articles

Zn in 7WU0
Zn in 7WTZ
Zn in 7WTX
Zn in 7WTW
Zn in 7WT5
Zn in 7WTU
Zn in 7WTV
Zn in 7WTT
Zn in 7WT4
Zn in 7WT3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy