Atomistry » Ytterbium » PDB 5l2m-7jww » 5n3w
Atomistry »
  Ytterbium »
    PDB 5l2m-7jww »
      5n3w »

Ytterbium in PDB 5n3w: Crystal Structure of LTA4H Bound to A Selective Inhibitor Against LTB4 Generation

Enzymatic activity of Crystal Structure of LTA4H Bound to A Selective Inhibitor Against LTB4 Generation

All present enzymatic activity of Crystal Structure of LTA4H Bound to A Selective Inhibitor Against LTB4 Generation:
3.3.2.6;

Protein crystallography data

The structure of Crystal Structure of LTA4H Bound to A Selective Inhibitor Against LTB4 Generation, PDB code: 5n3w was solved by C.T.Wong, C.M.Low, R.J.Snelgrove, S.A.Hare, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 65.65 / 2.30
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 78.250, 87.050, 99.960, 90.00, 90.00, 90.00
R / Rfree (%) 23.9 / 28.8

Other elements in 5n3w:

The structure of Crystal Structure of LTA4H Bound to A Selective Inhibitor Against LTB4 Generation also contains other interesting chemical elements:

Zinc (Zn) 1 atom

Ytterbium Binding Sites:

The binding sites of Ytterbium atom in the Crystal Structure of LTA4H Bound to A Selective Inhibitor Against LTB4 Generation (pdb code 5n3w). This binding sites where shown within 5.0 Angstroms radius around Ytterbium atom.
In total only one binding site of Ytterbium was determined in the Crystal Structure of LTA4H Bound to A Selective Inhibitor Against LTB4 Generation, PDB code: 5n3w:

Ytterbium binding site 1 out of 1 in 5n3w

Go back to Ytterbium Binding Sites List in 5n3w
Ytterbium binding site 1 out of 1 in the Crystal Structure of LTA4H Bound to A Selective Inhibitor Against LTB4 Generation


Mono view


Stereo pair view

A full contact list of Ytterbium with other atoms in the Yb binding site number 1 of Crystal Structure of LTA4H Bound to A Selective Inhibitor Against LTB4 Generation within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Yb702

b:61.2
occ:1.00
OD2 A:ASP481 2.3 42.0 1.0
O A:HOH977 2.4 41.2 1.0
OD1 A:ASP481 2.6 33.4 1.0
CG A:ASP481 2.8 37.9 1.0
CB A:ASP481 4.3 36.6 1.0
OD1 A:ASP482 4.4 22.0 1.0
O A:HOH1006 4.5 27.8 1.0
OD2 A:ASP482 4.5 23.1 1.0
CG A:ASP482 4.8 22.9 1.0
CB A:LYS479 4.8 22.4 1.0
CG A:LYS479 4.9 22.0 1.0

Reference:

C.M.Low, S.Akthar, D.F.Patel, S.Loser, C.T.Wong, P.L.Jackson, J.E.Blalock, S.A.Hare, C.M.Lloyd, R.J.Snelgrove. The Development of Novel LTA4H Modulators to Selectively Target LTB4 Generation. Sci Rep V. 7 44449 2017.
ISSN: ESSN 2045-2322
PubMed: 28303931
DOI: 10.1038/SREP44449
Page generated: Wed Dec 16 02:42:14 2020

Last articles

Zn in 7M6U
Zn in 7NNG
Zn in 7NEE
Zn in 7NEU
Zn in 7M3K
Zn in 7KWD
Zn in 7KYH
Zn in 7KNG
Zn in 7KY2
Zn in 7KYF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy