Atomistry » Ytterbium » PDB 3ftz-5i2s » 3fud
Atomistry »
  Ytterbium »
    PDB 3ftz-5i2s »
      3fud »

Ytterbium in PDB 3fud: Leukotriene A4 Hydrolase in Complex with N-Methyl-1-(2-Thiophen-2- Ylphenyl)Methanamine

Enzymatic activity of Leukotriene A4 Hydrolase in Complex with N-Methyl-1-(2-Thiophen-2- Ylphenyl)Methanamine

All present enzymatic activity of Leukotriene A4 Hydrolase in Complex with N-Methyl-1-(2-Thiophen-2- Ylphenyl)Methanamine:
3.3.2.6;

Protein crystallography data

The structure of Leukotriene A4 Hydrolase in Complex with N-Methyl-1-(2-Thiophen-2- Ylphenyl)Methanamine, PDB code: 3fud was solved by D.R.Davies, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.00 / 2.20
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 77.942, 87.140, 99.106, 90.00, 90.00, 90.00
R / Rfree (%) 19.2 / 23.8

Other elements in 3fud:

The structure of Leukotriene A4 Hydrolase in Complex with N-Methyl-1-(2-Thiophen-2- Ylphenyl)Methanamine also contains other interesting chemical elements:

Zinc (Zn) 1 atom

Ytterbium Binding Sites:

The binding sites of Ytterbium atom in the Leukotriene A4 Hydrolase in Complex with N-Methyl-1-(2-Thiophen-2- Ylphenyl)Methanamine (pdb code 3fud). This binding sites where shown within 5.0 Angstroms radius around Ytterbium atom.
In total only one binding site of Ytterbium was determined in the Leukotriene A4 Hydrolase in Complex with N-Methyl-1-(2-Thiophen-2- Ylphenyl)Methanamine, PDB code: 3fud:

Ytterbium binding site 1 out of 1 in 3fud

Go back to Ytterbium Binding Sites List in 3fud
Ytterbium binding site 1 out of 1 in the Leukotriene A4 Hydrolase in Complex with N-Methyl-1-(2-Thiophen-2- Ylphenyl)Methanamine


Mono view


Stereo pair view

A full contact list of Ytterbium with other atoms in the Yb binding site number 1 of Leukotriene A4 Hydrolase in Complex with N-Methyl-1-(2-Thiophen-2- Ylphenyl)Methanamine within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Yb702

b:27.9
occ:1.00
O A:ACT801 2.3 18.6 1.0
OD2 A:ASP481 2.4 18.0 1.0
OD1 A:ASP481 2.6 17.9 1.0
CG A:ASP481 2.8 19.9 1.0
OXT A:ACT801 2.9 19.4 1.0
C A:ACT801 3.0 19.0 1.0
O A:HOH623 4.3 15.0 1.0
CB A:ASP481 4.3 19.1 1.0
OD2 A:ASP482 4.4 19.1 1.0
CH3 A:ACT801 4.4 18.1 1.0
OD1 A:ASP482 4.7 20.5 1.0
CB A:LYS479 4.7 16.4 1.0
CG A:ASP482 4.8 19.0 1.0

Reference:

D.R.Davies, B.Mamat, O.T.Magnusson, J.Christensen, M.H.Haraldsson, R.Mishra, B.Pease, E.Hansen, J.Singh, D.Zembower, H.Kim, A.S.Kiselyov, A.B.Burgin, M.E.Gurney, L.J.Stewart. Discovery of Leukotriene A4 Hydrolase Inhibitors Using Metabolomics Biased Fragment Crystallography. J.Med.Chem. V. 52 4694 2009.
ISSN: ISSN 0022-2623
PubMed: 19618939
DOI: 10.1021/JM900259H
Page generated: Sat Oct 12 21:07:39 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy